Characteristic | Description |
---|---|
Active Ingredient | Orlistat 120 mg |
Indication | Obesity Management |
Dosage Form | Capsule |
Administration Route | Oral |
Approval Status | FDA Approved |
Learn More About Xenical |
Xenical (Orlistat 120 mg) targets obesity in adults and adolescents. It works by inhibiting lipase, a gastrointestinal enzyme. This enzyme breakdowns dietary fats into smaller components, facilitating absorption. By blocking this process, Xenical reduces fat absorption by about 30%. This results in weight loss, a significant reduction in body mass index (BMI), and improved lipid profile. Xenical 120 mg supports lifestyle modifications, including diet and physical activity. Prescribers recommend its use for overweight individuals with comorbidities, such as hypertension, type 2 diabetes, or dyslipidemia.
Off-Label Uses
Xenical’s primary use targets obesity, but clinicians sometimes use it off-label. In polycystic ovary syndrome (PCOS), Xenical can mitigate symptoms. By promoting weight loss, it helps balance hormone levels. In nonalcoholic fatty liver disease (NAFLD), Xenical aids liver function. Weight reduction improves liver enzymes and hepatic steatosis. Although not universally recommended, some physicians suggest Xenical for weight maintenance post-bariatric surgery. It may stabilize weight by controlling dietary fat absorption. Furthermore, Xenical can support cardiovascular risk management, given its impact on cholesterol and weight.
Xenical Contraindications
Xenical 120 mg holds specific contraindications. Patients with chronic malabsorption syndrome should avoid it, as it exacerbates nutrient deficiencies. Individuals with cholestasis, a liver disorder impeding bile flow, should also steer clear. Hypersensitivity to orlistat or any formulation component warrants abstention. Pregnant or lactating women should not use Xenical. Weight loss drugs can potentially harm fetal and neonatal development. Additionally, those with existing kidney disease should exercise caution. Xenical may increase urinary oxalate, aggravating kidney stones. Medical professionals must evaluate patient history before prescribing Xenical 120 mg.
Xenical Interactions
Xenical 120 mg interacts with various medications. It reduces the absorption of fat-soluble vitamins (A, D, E, K). Patients should supplement their diet with a multivitamin. Warfarin, an anticoagulant, requires monitoring when combined with Xenical. The alteration in vitamin K absorption can affect INR levels. Cyclosporine, an immunosuppressant, displays reduced efficacy with Xenical. Blood levels should be checked frequently. The diabetes drug levothyroxine may also interact. Xenical delays its absorption, necessitating dosage adjustments. Constant communication with healthcare providers ensures safe Xenical 120 mg use alongside other treatments.
Adverse Effects
Xenical 120 mg use may cause adverse effects. Gastrointestinal disturbances are most common. These include oily spotting, flatulence with discharge, and fecal urgency. Such events usually occur within the first few months. The side effects are diet-dependent. Reducing dietary fat can minimize symptoms. Less frequent reactions involve headaches, upper respiratory infections, and fatigue. Rarely, severe liver injury may occur. Users should report symptoms like jaundice or abdominal pain immediately. Overall, Xenical 120 mg is well-tolerated when used as directed. Regular monitoring by healthcare professionals enhances safety and efficacy.
Xenical Over The Counter
Xenical 120 mg remains prescription-only in many regions. However, a lower-dose version, Alli (Orlistat 60 mg), is available over the counter. Alli suits adults aiming for modest weight loss. It should accompany a reduced-calorie, low-fat diet. Though less potent than Xenical 120 mg, Alli demonstrates similar efficacy in clinical trials. Nonetheless, medical consultation before use remains prudent. A healthcare provider can determine suitability and advise on dosage and duration. The over-the-counter option expands accessibility while maintaining safety. With responsible use, Alli complements weight management strategies effectively.
Common Interactions | Description |
---|---|
Warfarin | Monitor INR levels regularly. |
Cyclosporine | Check blood levels frequently. |
Levothyroxine | Adjust dosage as necessary. |
Xenical 120 mg remains a pivotal tool in combating obesity. By addressing dietary fat absorption, it aids weight management. Healthcare providers should carefully assess potential interactions and contraindications. A multidisciplinary approach, involving dietary and lifestyle changes, enhances outcomes. Xenical 120 mg represents a viable solution for individuals struggling with weight-related health issues. When used responsibly, it facilitates healthier living and reduces the burden of obesity-related conditions.
Data source:
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